SPI Best Paper Award
Awardees:
2021
Jeremy Sousa*, Baltazar Cá*, Ana Raquel Maceiras, Luisa Simões-Costa, Kaori L Fonseca, Ana Isabel Fernandes, Angélica Ramos, Teresa Carvalho, Leandro Barros, Carlos Magalhães, Álvaro Chiner-Oms, Henrique Machado, Maria Isabel Veiga, Albel Singh, Rui Pereira, António Amorim, Jorge Vieira, Cristina P Vieira, Apoorva Bhatt, Fernando Rodrigues, Pedro N S Rodrigues, Sebastien Gagneux, António Gil Castro, João Tiago Guimarães, Helder Novais Bastos, Nuno S Osório, Iñaki Comas, Margarida Saraiva.
Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production.
Published in Nat Commun. 2020 Apr 23;11(1):1949
2020
Cristina Godinho-Silva*, Rita G. Domingues*, Miguel Rendas, Bruno Raposo, Hélder Ribeiro, Joaquim Alves da Silva, Ana Vieira, Rui M. Costa, Nuno L. Barbosa-Morais, Tânia Carvalho, Henrique Veiga-Fernandes.
Light-entrained and brain-tuned circadian circuits regulate ILC3 and gut homeostasis.
Published in Nature 2019 Oct 574(7777):254-258
2019
Sofia Mensurado, Margarida Rei, Telma Lança, Marianna Ioannou, Natacha Gonçalves-Sousa, Hiroshi Kubo, Marie Malissen, Venizelos Papayannopoulos, Karine Serre*, Bruno Silva-Santos*.
Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress.
Published in PLoS Biol. 2018 May 11;16(5):e2004990
Elva Bonifácio Andrade, Ana Magalhães, Ana Puga, Madalena Costa, Joana Bravo, Camila Cabral Portugal, Adília Ribeiro, Margarida Correia-Neves, Augusto Faustino, Arnaud Firon, Patrick Trieu-Cuot, Teresa Summavielle, Paula Ferreira .
A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection.
Published in Nat Commun. 2018 Aug 7;9(1):3138
2018
Vânia Cardoso*, Julie Chesné*, Hélder Ribeiro, Bethania García-Cassani, Tânia Carvalho, Tiffany Bouchery, Kathleen Shah, Nuno L. Barbosa-Morais, Nicola Harris, Henrique Veiga-Fernandes.
Neuronal regulation of type 2 innate lymphoid cells via neuromedin U.
Published in Nature. 2017 Sep 14;549(7671):277-281
2017
Sales Ibiza, Bethania García-Cassani et al.
Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence.
Instituto de Medicina Molecular, Lisboa
Published in Nature, 2016 Jul 21;535(7612):440-443
2016
Rita Domingues et al.
NFIL3 orchestrates the emergence of commom helper innate lymphoid cell precursors.
Instituto de Medicina Molecular, Lisboa
Published in Cell Reports, 2015 Mar 31;10(12):2043-54
2014
Manuela Ferreira et al.
Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity.
Published in Nature. 2014 Apr 3;508(7494):123-7.
2013
Patel A, Harker N, Moreira-Santos L, Ferreira M, Alden K, Timmis J, Foster K, Garefalaki A, Pachnis P, Andrews P, Enomoto H, Milbrandt J, Pachnis V, Coles MC, Kioussis D, Veiga-Fernandes H.
Instituto de Medicina Molecular, Lisboa.
“Differential RET Signaling Pathways Drive Development of the Enteric Lymphoid and Nervous systems”
Published in the Science signaling, 2012 Jul 31;5(235):ra55
2012
Priscila P Zenatti, Daniel Ribeiro, Wenqing Li, Linda Zuurbier, Milene C Silva, Maddalena Paganin, Julia Tritapoe, Julie A Hixon, André B Silveira, Bruno A Cardoso, Leonor M Sarmento, Nádia Correia, Maria L Toribio, Jörg Kobarg, Martin Horstmann, Rob Pieters, Silvia R Brandalise, Adolfo A Ferrando, Jules P Meijerink, Scott K Durum, J Andrés Yunes & João T Barata
Instituto de Medicina Molecular, Lisboa.
“Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia”
Published in the Nature Genetics 2011; Vol. 43;Nº. 10:932-939.
2011
Santiago Zelenay, Marie-Louise Bergman, Ricardo Sousa Paiva, Andreia C. Lino, Ana C. Martins, João H. Duarte, Maria F. Moraes-Fontes, Angelina M. Bilate, Juan J. Lafaille and Jocelyne Demengeot
Instituo Gulbenkian de Ciência, Oeiras.
“Intrathymic differentiation of adaptive Foxp3+ regulatory t cells upon peripheral proinflammatory immunization”
Published in the Journal of Immunology. 2010; 185:3829-3833.
2010
Andrea Cruz, Fraga AG, Fountain JJ, Rangel-Moreno J, Torrado E, Saraiva M, Pereira DR, Randall TD, Pedrosa J, Cooper AM, Castro AG.
Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga.
“Pathological role for IL-17 in mice infected with Mycobacterium tuberculosis receiving repeated post-exposure vaccination with BCG”
Published in the Journal of Experimental Medicine. 2010; 207:1609-16.
2009
Julie Ribot, deBarros A, Pang DJ, Neves JF, Peperzak V, Roberts SJ, Girardi M, Borst J, Hayday AC, Pennington DJ, Silva-Santos B.
Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa.
“CD27 is a thymic determinant of the balance between Interferon-g- and Interleukin-17-producing gd T cell subsets”
Published in Nature Immunology 2009;10:427-436.
